Advances in Genome-Wide Association Studies [GE03]

Course highlights

EC points

1.4

Start date

03-02-2020

End date

07-02-2020

Course days

Monday to Friday, assignment due Friday 14/02 at 17:00

Faculty

Linda Broer - Erasmus MC (NL), Katerina Trajanoska - Erasmus MC (NL), Cindy Boer - Erasmus MC (NL), Christian Benner - University of Helsinki (FIN)/Regeneron Pharmaceuticals (USA), Felix Day - University of Cambridge (UK), Fernando Rivadeneira - Erasmus MC, NL

Course fee

€ 870

Location

Erasmus MC, Rotterdam NL

Level

Intermediate

Prerequisites

Understanding of genetic epidemiology and statistics (regression analysis and maximum likelihood estimation); experience in working with the Linux command line interface, e.g. at the level of the "Linux for Scientists" course (GE14 or previously SC09).

Disciplines

  • Genetic Epidemiology

Application

How to apply

Detailed information about this course:

Description

This 5-day advanced course aims to give an overview of new developments in the field of genome wide association studies for those with a background in genetics, epidemiology or statistics. In the first part of the course, issues concerning the design and analysis of genome-wide association (GWA) analysis will be covered using standard software such as Plink and genABEL. This part will include quality control, hands-on GWA analysis of quantitative and binary traits, methods to detect and correct for stratification, and to model epistastasis. In the second part we will extend to an integrated approach of data analysis including eSNPs and new developments in the analysis of whole sequence data.


Finally, we will discuss the perspectives for genetic testing in clinical practice. A major part of the teaching programme consists of hands-on exercises.

Objectives

Gain insight in new developments in the field of genome wide association studies.

Participant profile

Epidemiologists, geneticists, biostatisticians, investigators/physicians involved in clinical and pharmacological research.

Assessment

Assignment(s)


Reduction on fees

PLEASE NOTE THIS DOES NOT APPLY TO THE RESEARCH MASTERS (120 EC points)

50% reduction on our fees for participating institutes of NIHES

This 50% reduction is offered to participants formally appointed at the departments or sections participating in NIHES.

University Medical Center Rotterdam/Erasmus University Rotterdam:

  • Department of Epidemiology
  • Department of Public Health
  • Department of Psychiatry, Section of Medical Psychology and Psychotherapy
  • Department of Child and Adolescent Psychiatry/Psychology
  • Department of Medical Informatics
  • Department of General Practice
  • Erasmus School of Health Policy & Management
  • Generation R

50% reduction on our fees for NIHES affiliated partners

This 50% reduction is offered to participants formally appointed at the following NIHES affiliated partners:

University Medical Center Rotterdam/Erasmus University Rotterdam, departments of:

  • Dermatology
  • General Paediatrics
  • Plastic and Reconstructive Surgery
  • Rehabilitation Medicine

UMIT, Department of Public Health, Health Services Research and Health Technology Assessment.

25% reduction on our fees for Erasmus MC employees

For participants formally appointed at all departments of Erasmus MC (except the departments mentioned above).

25% reduction for all (international) PhD students
Please upload proof of enrollment as a PhD student in the application form and state the name of your tutor on the application form (remarks field).

25% reduction on our course fees (maximum 3 EC points per academic year) for all NIHES alumni
Please state that you are a NIHES alumnus/alumna and the academic year you graduated (remarks field). Please note that the reduction on fees for alumni does not apply to the Erasmus Summer Programme.