Causal Inference [ESP48]

Course highlights

EC points

1.4

Start date

06-08-2018

End date

10-08-2018

Course days

Monday to Friday (5 full days)

Faculty

Prof. Miguel Hernán, MD and Sonja Swanson, ScD

Course fee

€ 1190

Location

Erasmus MC, Rotterdam NL

Level

Advanced

Prerequisites

Intermediate-level courses in epidemiology and biostatistics. Previous experience in epidemiologic research recommended.
Ideally, NIHES Master students should take the course EP01 Principles in Causal Inference before this course.

Disciplines

  • Methodology

Application

Go to the ESP website

Detailed information about this course:

Description

Faculty: Prof. Miguel Hernán, MD & Sonja Swanson, ScD


The goal of many epidemiologic studies is to quantify the causal effect of a treatment (or exposure) on an outcome. In contrast, commonly used statistical methods provide measures of association that may lack a causal interpretation even when the investigator adjusts for all potential confounders in the analysis of a properly designed study.


To eliminate the discordance between the causal goals and the associational methods in epidemiology, it is necessary to a) formally define causal concepts such as causal effect and confounding, b) identify the conditions required to estimate causal effects, and c) use analytical methods that, under those conditions, provide estimates that can be endowed with a causal interpretation. These so-called g-methods can be used under less restrictive conditions than traditional statistical methods. For example, g-methods allow one to estimate the causal effect of a time-varying treatment in the presence of time-varying confounders that are affected by the treatment.


This course combines counterfactual theory and graph theory to present an integrated framework for causal inference from observational data, with a special emphasis on complex longitudinal data. The course presents the latest methodologic developments for the design and analysis of longitudinal studies. Specifically, the course will introduce the three g-methods (inverse probability weighting of marginal structural models; parametric g-formula; and g-estimation of structural nested models) in the setting of time-fixed treatments, and demonstrate inverse probability weighting for addressing causal questions regarding static and dynamic treatment strategies.

Objectives

The student is able to:

  • Recognize and formulate well defined questions concerning causal effects;
  • Use causal diagrams to represent a priori subject-matter knowledge and assumptions;
  • Identify the settings in which conventional methods for data analysis are inadequate;
  • Use provided software to estimate causal effects using g-methods.

Participant profile

The course is intended for health researchers or other data scientists who will use observational studies to estimate causal effects as part of their current or future professional career. Examples include: epidemiologists, (bio-)statisticians, and other clinical or public health researchers.

Assessment

Attendance


Reduction on fees

PLEASE NOTE THIS DOES NOT APPLY TO THE RESEARCH MASTERS (120 ECTS)

50% reduction on our fees for participating institutes of NIHES

This 50% reduction is offered to participants formally appointed at the departments or sections participating in NIHES.

University Medical Center Rotterdam/Erasmus University Rotterdam:

  • Department of Epidemiology
  • Department of Public Health
  • Department of Psychiatry, Section of Medical Psychology and Psychotherapy
  • Department of Child and Adolescent Psychiatry/Psychology
  • Department of Medical Informatics
  • Department of General Practice
  • Erasmus School of Health Policy & Management
  • Generation R

50% reduction on our fees for NIHES affiliated partners

This 50% reduction is offered to participants formally appointed at the following NIHES affiliated partners:

University Medical Center Rotterdam/Erasmus University Rotterdam, departments of:

  • Dermatology
  • General Paediatrics
  • Plastic and Reconstructive Surgery
  • Rehabilitation Medicine

Institute of Medical Education Research Rotterdam (iMERR)

Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital

  • Department of Cancer Epidemiology

25% reduction on our fees for partner institutes of NIHES

For participants formally appointed at the following departments, institutes:

  • Departments of Erasmus MC (except the departments mentioned above)
  • Addiction Research Institute (IVO)
  • Integraal Kankercentrum Zuid (IKZ)
  • Pallas Health Research and Consultancy
  • Municipal Health Service Amsterdam (GGD Amsterdam)
  • Municipal Health Service Rotterdam (GGD Rotterdam)
  • Havenpolikliniek
  • Admiraal De Ruyter Ziekenhuis

25% reduction for all (international) PhD students
Please state your tutor’s name and email address on the application form (remarks field).

25% reduction on our course fees (maximum 3 EC points per academic year) for all NIHES alumni
Please state that you are a NIHES alumnus/alumna and the academic year you graduated (remarks field).