Causal Mediation Analysis [ESP69]

Course highlights

EC points

1.4

Start date

22-08-2022

End date

26-08-2022

Course days

Monday to Friday (5 full days)

Faculty

Dr. Linda Valeri

Course fee

€ 988

Location

Online

Level

Advanced

Prerequisites

Knowledge of implementation and interpretation of linear and logistic regression is required.

Disciplines

  • Advanced Statistics

Application

Go to the ESP website

Detailed information about this course:

Description

NOTE: THIS COURSE IS ONLINE, COURSE TIMETABLE MAY DEVIATE FROM STANDARD COURSE TIMES

Faculty: Linda Valeri, PhD

The course covers recent developments in causal mediation analysis and provide practical tools to implement these techniques. Mediation analysis concerns assessing the mechanisms and pathways by which causal effects operate. The course covers the relationship between traditional methods for mediation in epidemiology and the social sciences and new methods in causal inference. For dichotomous, continuous, and time-to-event outcomes, we discuss when the standard approaches to mediation analysis are valid. Using ideas from causal inference and natural direct and indirect effects, alternative mediation analysis techniques are described when the standard approaches do not work. The no-confounding assumptions needed for these techniques are described.

SAS, R and Stata macros to implement these techniques are covered and distributed to course participants. The use and implementation of sensitivity analysis techniques to assess the how sensitive conclusions are to violations of assumptions are covered. Discussion will be given to how such mediation analysis approaches can be extended to settings in which data come from a case-control study design. The methods will be illustrated by various applications.

The course will employ a combination of lecture, discussion, and software demonstration. Powerpoint slides are used to present material in lecture form. Extensive printed notes are available for students. A wide variety of examples from epidemiology and the social sciences will be used to illustrate the techniques and approaches. Ample time is given for discussion and questions. A variety of software packages will be discussed. Students will have worked exercises that they can complete on their own.


Timetable
15.30 - 17.00 hrs Live lab (attendance mandatory)
17.00 - 18.00 hrs Office hours on Tuesday, Wednesday, and Thursday.


Objectives

  • Understand when traditional methods for mediation fail
  • Learn the concepts about mediation from causal inference
  • Learn methods and sensitivity analysis techniques for mediation
  • Develop facility with use of software for mediation

Participant profile

Anyone who wants to learn about mediation analysis and is familiar with linear and logistic regression.

Assessment

Attendance


Reduction on fees

PLEASE NOTE THIS DOES NOT APPLY TO THE RESEARCH MASTERS (120 EC points)

No fees are charged for participation of Erasmus MC PhD candidates

Please note that in case of cancellation or no show, the cancellation policy applies based on the full course fee.

 

25% reduction for all (international) PhD students without formal appointment at Erasmus MC

Upon receipt of your application you will receive a request to upload proof of enrollment as a PhD student.