Introduction to Genome-Wide Association Studies [EL017]

Course highlights

EC points

1.4

Start date

06-02-2023

End date

10-02-2023

Course days

Monday to Friday, assignment due after the course

Faculty

Linda Broer - Erasmus MC (NL), Katerina Trajanoska - Erasmus MC (NL), Cindy Boer - Erasmus MC (NL), Christian Benner - University of Helsinki (FIN)/Regeneron Pharmaceuticals (USA), Felix Day - University of Cambridge (UK), Fernando Rivadeneira - Erasmus MC, NL

Course fee

€ 910

Location

Erasmus MC, Rotterdam NL

Level

Intermediate

Prerequisites

Understanding of genetic epidemiology and statistics (regression analysis and maximum likelihood estimation); experience in working with the Linux command line interface, e.g. at the level of the "Linux for Scientists" course (EL016 or previously SC09).

Disciplines

  • Genetic Epidemiology

Application

How to apply

Detailed information about this course:

Description

This 5-day advanced course aims to give an overview of new developments in the field of genome wide association studies for those with a background in genetics, epidemiology or statistics. In the first part of the course, issues concerning the design and analysis of genome-wide association (GWA) analysis will be covered using standard software such as Plink and genABEL. This part will include quality control, hands-on GWA analysis of quantitative and binary traits, methods to detect and correct for stratification, and to model epistastasis. In the second part we will extend to an integrated approach of data analysis including eSNPs and new developments in the analysis of whole sequence data.

Finally, we will discuss the perspectives for genetic testing in clinical practice. A major part of the teaching programme consists of hands-on exercises.

Objectives

Gain insight in new developments in the field of genome wide association studies.

Participant profile

Epidemiologists, geneticists, biostatisticians, investigators/physicians involved in clinical and pharmacological research.

Assessment

Assignment(s), Attendance


Reduction on fees

PLEASE NOTE THIS DOES NOT APPLY TO THE RESEARCH MASTERS (120 EC points)

No fees are charged for  Erasmus MC PhD candidates, provided they have an account in Hora Finita, the Erasmus University PhD registration system.

Please note that in case of cancellation or no show, the cancellation policy applies based on the full course fee.

 

25% reduction for all (international) PhD candidates without formal appointment at Erasmus MC

Upon receipt of your application you will receive a request to upload proof of enrollment as a PhD candidate.