Genetic-epidemiologic Research Methods [GE02]

Course highlights

EC points




Course days

Monday to Friday during the first three weeks (course starts on Wednesday). The last week is a study week.


Prof. Fernando Rivadeneira, MD, PhD, Linda Broer, PhD, Prof. Simon Heath, PhD

Course fee

€ 1680


Erasmus MC, Rotterdam NL




Genome Wide Association Analysis (ESP74), Principles of Genetic Epidemiology (ESP43), Genomics in Molecular Medicine (ESP57), Biostatistical Methods I: Basic Principles (CC02), and Linux for Scientists (GE14)

The Linux for Scientists course (GE14) takes place immediately before GE02. You are expected to have sufficient knowledge of Linux if you want to follow GE02 without participating in GE14.


  • Methodology

Resit date



How to apply

Detailed information about this course:


The aim of this course is to introduce participants to the basic principles of genetic epidemiologic reserach. The first part of the course is dedicated to explaining general concepts of genetic epidemiology; then followed by the fundamental methods used for the analysis of binary traits, covering the basics of probability theory, hypothesis testing, risk calculation in families, and principles of segregation analysis. The second part of the course focuses on the genetics of quantitative traits, covering the concept and estimation of heritability and basic quantitative trait linkage analysis using modern genetic analysis software such as SOLAR and MERLIN. In the third part of the course, diverse aspects of study design in genetic epidemiology will be covered. This will be illustrated by practical examples and an assignment to develop a study. During the third week of the course, students will work in groups on this assignment, and will prepare a presentation. The last week is the preparation week for the examination.


Introduce participants to the basic principles of genetic epidemiological research.


Written exam, Assignment(s)

Reduction on fees


50% reduction on our fees for participating institutes of NIHES

This 50% reduction is offered to participants formally appointed at the departments or sections participating in NIHES.

University Medical Center Rotterdam/Erasmus University Rotterdam:

  • Department of Epidemiology
  • Department of Public Health
  • Department of Psychiatry, Section of Medical Psychology and Psychotherapy
  • Department of Child and Adolescent Psychiatry/Psychology
  • Department of Medical Informatics
  • Department of General Practice
  • Erasmus School of Health Policy & Management
  • Generation R

50% reduction on our fees for NIHES affiliated partners

This 50% reduction is offered to participants formally appointed at the following NIHES affiliated partners:

University Medical Center Rotterdam/Erasmus University Rotterdam, departments of:

  • Dermatology
  • General Paediatrics
  • Plastic and Reconstructive Surgery
  • Rehabilitation Medicine

UMIT, Department of Public Health, Health Services Research and Health Technology Assessment.

25% reduction on our fees for Erasmus MC employees

For participants formally appointed at all departments of Erasmus MC (except the departments mentioned above).

25% reduction for all (international) PhD students
Please upload proof of enrollment as a PhD student in the application form and state the name of your tutor on the application form (remarks field).

25% reduction on our course fees (maximum 3 EC points per academic year) for all NIHES alumni
Please state that you are a NIHES alumnus/alumna and the academic year you graduated (remarks field). Please note that the reduction on fees for alumni does not apply to the Erasmus Summer Programme.