Genetic-epidemiologic Research Methods [GE02]

Course highlights

EC points




Course days

Monday to Friday during the first three weeks (course starts on Wednesday). The last week is a study week.


Prof. Fernando Rivadeneira, MD, PhD, Linda Broer, PhD, Prof. Simon Heath, PhD

Course fee

€ 1680


Erasmus MC, Rotterdam NL




Genome Wide Association Analysis (ESP74), Principles of Genetic Epidemiology (ESP43), Genomics in Molecular Medicine (ESP57), Biostatistical Methods I: Basic Principles (CC02), and Linux for Scientists (GE14)

The Linux for Scientists course (GE14) takes place immediately before GE02. You are expected to have sufficient knowledge of Linux if you want to follow GE02 without participating in GE14.


  • Methodology


How to apply

Detailed information about this course:


The aim of this course is to introduce participants to the basic principles of genetic epidemiologic reserach. The first part of the course is dedicated to explaining general concepts of genetic epidemiology; then followed by the fundamental methods used for the analysis of binary traits, covering the basics of probability theory, hypothesis testing, risk calculation in families, and principles of segregation analysis. The second part of the course focuses on the genetics of quantitative traits, covering the concept and estimation of heritability and basic quantitative trait linkage analysis using modern genetic analysis software such as SOLAR and MERLIN. In the third part of the course, diverse aspects of study design in genetic epidemiology will be covered. This will be illustrated by practical examples and an assignment to develop a study. During the third week of the course, students will work in groups on this assignment, and will prepare a presentation. The last week is the preparation week for the examination.


Introduce participants to the basic principles of genetic epidemiological research.


Written exam, Assignment(s)

Reduction on fees

PLEASE NOTE: This does not apply to the fee of the research master programmes (120 EC points)

No fees are charged for  Erasmus MC PhD candidates, provided they have an account in Hora Finita, the Erasmus University PhD registration system. When submitting the application, you can state that someone else pays your tuition fee.

In case of cancellation or no show, the cancellation policy applies based on the full course fee.


25% reduction for all (international) PhD candidates without formal appointment at Erasmus MC

Upon receipt of your application you will receive a request to upload proof of enrollment as a PhD candidate.